Researchers Job Offers

VICE-RECTOR in Charge of the School of Natural Sciences / for Finance and Research Projects at the Adam Mickiewicz University, Poznań announces a competition for the position of: 

Post-Doctoral Researcher 

at the Center for Development of Gene Therapies TREAT-EXP

in the project FENG.02.01-IP.05-M038/25, TREAT-EXP: Development of therapeutic strategies for human genetic diseases caused by nucleotide repeat expansions.

The FENG.02.01-IP.05-M038/25 project is carried out within the 2.1 MAB FENG call 2/2025  programme of the Foundation for Polish Science co-financed by the European Union under the European Funds for Smart Economy 2021-2027 (FENG).

A post-doctoral researcher position in a research group at the newly established Center for the Development of Gene Therapies at Adam Mickiewicz University.

We are seeking a candidate interested in research in the following areas: understanding the molecular pathomechanisms of human diseases caused by nucleotide repeat expansions, generating transgenic cell models and iPS models, including genetic modification using CRISPR-Cas technology, imaging cells using confocal and superresolution microscopy, identifying biomarkers of studied diseases, and developing new therapeutic small-molecules and antisense oligonucleotides targeting mutated RNA molecules containin expanded repeats.

A brief project description can be found at: https://ibmib.web.amu.edu.pl/mab-feng-grant/

Anticipated job starting date: April 20, 2026

Fixed-term contract for 12 months, with the possibility of extension until December 31, 2029,

Monthly salary: PLN 13 866 gross

Requirements

Research Field

Biological sciences

Education Level

PhD or equivalent

Language

VICE-RECTOR in Charge of the School of Natural Sciences / for Finance and Research Projects at the Adam Mickiewicz University, Poznań announces a competition for the position of: 

Post-Doctoral Researcher 

at the Center for Development of Gene Therapies TREAT-EXP

in the project FENG.02.01-IP.05-M038/25, TREAT-EXP: Development of therapeutic strategies for human genetic diseases caused by nucleotide repeat expansions.

The FENG.02.01-IP.05-M038/25 project is carried out within the 2.1 MAB FENG call 2/2025  programme of the Foundation for Polish Science co-financed by the European Union under the European Funds for Smart Economy 2021-2027 (FENG).

A post-doctoral researcher position in a research group at the newly established Center for the Development of Gene Therapies at Adam Mickiewicz University.

We are seeking a postdoctoral researcher to join the research group of dr. hab. Michał Gdula to work on leveraging epigenetics to improve the effectiveness of genetic therapies for diseases caused by nucleotide repeat expansions (including myotonic dystrophies), within the framework of the International Research Agenda (MAB) FENG grant funded by the Foundation for Polish Science (FNP).

Dr. hab. Michał Gdula’s group is one of four teams participating in the TREAT-EXP project, led by Prof. Krzysztof Sobczak and funded by FNP with PLN 30 million over four years. The overarching goal of TREAT-EXP is to build a research platform to develop therapeutic strategies and identify active compounds targeting pathogenic products of mutated genes—either toxic RNA or toxic proteins—responsible for DM, FXPAC, and ALS.

The goal of Michał Gdula’s team is to increase the efficacy of therapies for DM1 and DM2 by modulating epigenetic regulation using modified antisense oligonucleotides (ASOs). DM1 is caused by a CTG expansion in the 3′UTR of the DMPK gene, while DM2 results from a CCTG expansion in an intron of the CNBP gene; the resulting toxic repeat-expanded RNA forms nuclear foci and sequesters MBNL proteins, leading to widespread alternative splicing defects and multiple multisystem symptoms.

The postdoc’s tasks will include characterizing the epigenetic landscape of DM-associated genes and mapping their regulatory elements in cellular models using genomic methods (e.g., ATAC-seq, CUT&RUN, Capture-C, Micro-C). Next, in collaboration with—and drawing on the expertise of—Prof. Sobczak’s group, ASOs will be designed to target selected regulatory elements in order to reduce DMPK/CNBP expression or increase the expression of MBNL genes.

We offer a position in a well-funded, interdisciplinary environment at the Center for Development of Gene Therapies (Adam Mickiewicz University), located in the modern Center for Advanced Technologies building.

A brief project description can be found at: https://ibmib.web.amu.edu.pl/mab-feng-grant/

Anticipated job starting date: May 1, 2026

Fixed-term contract for 12 months, with the possibility of extension until December 31, 2029,

Monthly salary: PLN 13 866 gross

Informal inquiries welcome: michal.gdula@amu.edu.pl

Requirements

Requirements

Adam Mickiewicz University in Poznań,

is looking for people for the position:

Chief Specialist - Knowledge Transfer Broker

In the project:

FENG.02.01-IP.05-M038/25, TREAT-EXP: Development of therapeutic strategies for human genetic diseases caused by nucleotide repeat expansion.

The FENG.02.01-IP.05-M038/25 project is carried out under Measure 2.1 MAB FENG, call 2/2025 of the Foundation for Polish Science, co-financed by the European Union from the funds of Priority 2 of the European Funds for Modern Economy 2021-2027 Programme (FENG).

Place of work: TREAT-EXP Gene Therapy Development Center in the building of the Center for Advanced Technologies of Adam Mickiewicz University

We offer:

• stable employment based on an employment contract for a period of 12 months with the possibility of extension until 31 December 2029;
• basic salary: PLN 6,930 gross;
• a wide package of non-wage benefits;
• development of professional qualifications;
• an atmosphere of respect and cooperation.

Application deadline: March 23, 2026

Requirements

More information about this job offer is available here: https://euraxess.ec.europa.eu/jobs/412016

In the last decade, two-dimensional van der Waals (vdW) materials, sparked by the “graphene revolution”, have become a major direction in modern technology development. At the same time, it has become increasingly clear that the mechanical fragility of 2D materials remains a key challenge for their scalable manufacturing and deployment in durable, real-world devices. In this context, several fundamental questions arise:

• Can we build an unambiguous and comprehensive empirical knowledge base that enables predictive design and fabrication of mechanically robust 2D vdW structures?
• What drives the discrepancy between the frequently reported, exceptionally high mechanical properties of vdW materials and today’s limited ability to manufacture durable structures at the technological scale?
• Do we have experimental tools for a consistent and complete mechanical assessment of vdW materials across the full thickness range, from bulk crystals, through thin layers and membranes, down to single molecular layers and their heterostructures?

The aim of this project is to address this challenge by investigating the nanomechanical properties of vdW materials, from macroscopic crystals to monolayers, using state-of-the-art optical tools. We will focus on transition-metal dichalcogenides (TMDCs) and perform a comprehensive study of how spatial confinement, interlayer twist, and strain affect the intrinsic elasticity of freestanding vdW structures and heterostructures.

To achieve this, we will develop a new, contact-free experimental platform based on fully optical inelastic light-scattering methods probing thermal and non-thermal phonons/acoustic waves. This approach will provide fundamental insight into the anisotropic elastic properties of TMDC monolayers and their stacked heterostructures (multilayers). The project’s breakthrough potential stems from a contact-free, non-destructive methodology based on Brillouin light scattering, which we will advance toward the technological and physical limits of precision.

The postdoctoral researcher’s tasks will include:

1. Setting up the experimental system for the fabrication of vdW monolayers and membranes.
2. Preparing samples from vdW single crystals (thin layers, membranes, and heterostructures).
3. Characterizing samples using Brillouin and Raman light-scattering techniques as well as SEM, TEM, and AFM microscopy.
4. Reporting results, preparing manuscripts for publication, and presenting findings at conferences and seminars.
5. Short-term international research visits (approx. one month per year) focused on sample fabrication (Spain, the Netherlands, and Japan).

Duration:2 years (with a possible 1-year extension after evaluation)

Basic gross salary: Approximately 14 500 PLN/month  (3 400 EUR/month)

Requirements

Vice-Rector for Finance and Research Projects

School of Natural Sciences

at the Adam Mickiewicz University, Poznań

announces a competition for the position of: 

assistant professor (post-doctoral researcher)

at the Faculty of Biology in the project OPUS "Multiomics and functional analyses in type 2 diabetes: targeting altered pathways and metabolic rearrangements." (number UMO-2024/53/B/NZ4/03103).

We are looking for a motivated researcher for the position of a postdoctoral fellow at the Laboratory of Stem Cell Biology and Regenerative Medicine, Adam Mickiewicz University in Poznan, in an OPUS project funded by the National Science Center, NCN. The successful candidate will study changes in pancreatic organoids derived from patients with type 2 diabetes using multi-omics techniques.

The research will be conducted using state-of-the-art techniques, including the differentiation of human stem cells into pancreatic beta cells and the production of organoids, advanced genome editing during differentiation, single-cell RNA sequencing, proteomics and lipidomics, functional assays, and microscopic imaging. Mastering all of these techniques is not necessary, as the project will be carried out in collaboration; however, there is an opportunity to learn more about them. The knowledge gained will be crucial for the development of cell and gene therapies for people with diabetes.

The laboratory is located in Poznań at the Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, which is one of the leading scientific institutions in Poland. This project will be carried out in close collaboration with the team of Prof. Małgorzata Borowiak at Adam Mickiewicz University and with two teams at the University of Helsinki, with the possibility of short-term internships. Our research group is a young, dynamic, and efficiently functioning team focused on cooperation, development, and mutual respect.

Selected publications of the team (prof. Borowiak/prof. Łałowski):

• Nature, 2012
• Nature Chemical Biology, 2009
• Nature Biotechnology, 2008
• Nature Communications 2018, 2017a, 2017b
• ScienceTranslational Medicine, 2020
• Cell Reports, 2018
• Frontiers in Pharmacology, 2018
• Diabetes, 2020
• Journal of Clinical Investigation, 2020
• EMBO rep, 2022
• Frontiers in Cell and Developmental Biology, 2021, 2023, 2025
• Nature Commun, 2023, 2025
• Experimental Molecular Medicine 2023, 2025

Type of an employment contract and expected duration of employment

Employment contract for a fixed term (until 02.2029). Full-time employment contract, initially for 6 months with the possibility of extension depending on the results for the remaining 30 months. During the period of receiving this remuneration, the postdoctoral fellow will not receive any other remuneration from funds awarded as direct costs from research projects financed under NCN competitions and will not receive remuneration from another employer based on an employment contract, including an employer based outside Poland.

Monthly salary - approx. 8987,00 PLN gross

Requirements