Event date: -

MTPR Seminar - prof. Marcin Nawotny

The Faculty of Physics cordially Invites You to Modern Trends in Physics Research Seminar. This week the Lecture on "Mechanisms of nucleic acid and recognition in DNA repair" will be given by prof. Marcin Nawotny from the International Institue of Molecular and Cell Biology, Medical University of Warsaw.
The event will take place on January 18, between 1 pm - 2 pm via Microsoft Teams.

Meeting ID: 365 747 902 735, Passcode: 6xhjAa
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DNA, which stores genetic information, is constantly subject to chemical damage. This distorts the blueprint of a living cell and can have catastrophic consequences. Life has evolved many DNA damage repair mechanisms that effectively recognize and remove lesions in genetic information. We are using structural biology to understand these mechanisms at the level of the individual protein atoms involved. In this talk, I will describe how a very general repair pathway, called nucleotide excision repair, localizes DNA damage in bacteria. I will also talk about the processing of branched DNA structures, which are intermediates of another general pathway called homologous recombination. Using these examples, I will also discuss some new general principles of nucleic acid recognition by proteins. I will also give a brief overview of recent developments in structural biology, particularly the development of cryo-electron microscopy.

Chairman: Prof. Jacek Gapiński

More information about the event is available on the MTPR website.